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However, there were differences in the reasons for drug discontinuation, as JAK inhibitors were mainly stopped for safety reasons and less commonly as a result of their ineffectiveness

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Together, the combination is marketed as a more effective weight loss tool than tirzepatide alone

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A straight diagonal line or FIC index = 1 indicates a clear additive effect between the two drugs, while a concave curve below the diagonal of the graph denotes a synergistic effect between the drugs